Ip-Table block-range-of-ip-addresses

To block 116.10.191.* addresses:

$ sudo iptables -A INPUT -s 116.10.191.0/24 -j DROP

To block 116.10.*.* addresses:

$ sudo iptables -A INPUT -s 116.10.0.0/16 -j DROP

To block 116.*.*.* addresses:

$ sudo iptables -A INPUT -s 116.0.0.0/8 -j DROP

Saving and restoring rules

$sudo aptitude install iptables-persistent
After the installation the initial setup will ask to save the current rules for IPv4 and IPv6, just select Yes and press enter for both.
If you make further changes to your iptables rules, remember to save them again using the same command as above. The iptables-persistent looks for the files rules.v4 and rules.v6 under /etc/iptables.